Αν επιθυμείτε μπορείτε να επιλέξετε κάποια υποκατηγορία:
Νοσήματα
Ρευματικά νοσήματα
Sjogren's syndrome
Sjogren’s syndrome (SS) is a chronic autoimmune disease which affects the salivary and lacrimal glands, as well as other exocrine glands, leading to functional exhaustion and dryness of mucous membranes, and is often associated with systemic extraglandular manifestations. SS can be primary or secondary to other autoimmune diseases (SLE, rheumatoid arthritis, scleroderma, biliary cirrhosis, etc.). In the primary syndrome, which is very rare in children, the sicca component is the dominant manifestation and is associated with lymphocytic infiltration of the lacrimal and salivary glands. In 50% of patients, connective tissue disease manifestations dominate.
6.2.1 EPIDEMIOLOGY
Frequency: SS is the most common, after RA, autoimmune disease. In the U.S., about 500.0000-2.000.000 people suffer from SS. In the rest of the world, the prevalence of SS is similar to the U.S.. In children, primary SS is rare. Only a few cases have been reported(Chudwin DS et al, 1981; Kraus A and Alarcon-Segovia D,...
Νοσήματα
Ρευματικά νοσήματα
Erosive osteoarthritis
INTRODUCTION
Erosive osteoarthritis (EOA) is a form of osteoarthritis, characterized by a greater extent of inflammation than the "traditional" osteoarthritis and the presence of radiographic bone erosions. EOA was first described by Kellgren and Moore (1952), but the term "erosive osteoarthritis" was established in 1966 by Peter and colleagues. Classically, EOA is described as osteoarthritis, which affects the DIP and PIP joints, often associated with synovitis and cyst formation, while others call it "inflammatory osteoarthritis» (Ehrlich, 1972). Most authors, however, consider EOA a variety of classical osteoarthritis, although there are conflicting views on whether it is a particular entity or a phase of nodal OA.
EPIDEMIOLOGY
Frequency
OA of the hands is estimated to affect 70% of those aged over 65 (Van Saase et al, 1989; Hochberg, 1991). EOA is believed to be a relatively uncommon clinical subgroup of osteoarthritis, occurring in 5-15% of patients with symptomatic OA of the hands (Ehrlich,...